CBD

What is CBD you ask? Well, let me give you a little background information on what it is, what it contains, and how it is produced. CBD is an abbreviation for cannabidiol, a prominent naturally-occurring cannabinoid component found in cannabis that comprises up to 40% of the plant. Cannabidiol is “a cannabinoid devoid of psychoactive effect.” Industrial hemp is naturally high in CBD and naturally low in THC, whereas most marijuana is just the opposite (high THC, low CBD). Natural CBD hemp oil is produced from hemp cultivars—which can be grown legally in dozens of countries and whose oil can be imported to the USA legally. These hemp plants are specially bred to contain high levels of naturally occurring Cannabidiol (CBD).

CBD does not contain psychoactive properties. This means, you CANNOT get ‘high’ or intoxicated by using these types of products. These products are used for their health benefits. The US Government makes many impressive claims about the benefits of CBD:

  • “Cannabinoids are potent antioxidants…they easily penetrate tissues giving them the ability to enter the central nervous system and brain.”
  • “Non-psychoactive Cannabinoids such as CBD are particularly advantageous as they are non-toxic…and exhibit unique antioxidant properties without the undesirable effects of THC.”
  • “The antioxidant strength of CBD is significantly greater than that of either Vitamin C or Vitamin E.

Dr. William Courtney a prominent Cannabis physician and researcher states: “I consider it the single most important dietary element, outside of water, that humans should have on a daily basis… it is a dietary essential.”

SHOULD I USE IT?

One of the hot topics of discussion nowadays is the legality and use of cannabidiol. Whether through oils, or other conventional means, that seems to be a topic that shows no signs of slowing down anytime soon. There are all sorts of studies and tests being done that show the benefits of using agricultural hemp, and one such way of obtaining its positive effects is through cannabidiol. Cannabidiol is an active cannabinoid that has been identified in agricultural hemp. It has a scope of medical applications that can be used for all sorts of means and has even been classified as an orphan drug status in the United States.

Cannabidiol, or CBD as many people know it as, has shown many different effects through peer-reviewed and intense study. It has shown to help in people with seizures and other neurological conditions. Not only that, but it can also be used as an antioxidant, neuroprotective agent, anti-inflammatory uses, an analgesic, has been shown to be anti-tumor, anti-psychotic, and even help with people in anxiety. More and more people are starting to realize the positive effects that cannabidiol can have, and is a great alternative to people who may not be fond of taking pills all the time and want to try something different, and maybe even a bit more natural.

For the sake of staying healthy, CBD Hemp Oil has shown time and time again that the people who take it see their symptoms diminish by an exorbitant amount. Not only that but it can also help reduce the said negative effects of THC. There is no sense of stopping cannabidiol in helping people as only the positive applications are applied in medication. If you know someone who may be going through a particular disease that CBD Hemp Oil has been known to help, give them information to see if agricultural hemp can work for them.

IS VAPING CBD BETTER?

In general, not all of the CBD you consume will directly affect your body: only a certain percentage will be able to enter your systemic circulation and produce its active effects. This percentage is referred to in science as “bioavailability,” and it strongly depends on the manner in which CBD is introduced to your system. For example, the oral bioavailability of CBD is roughly 15 percent. That means for every 100 milligrams of CBD that you eat, only 15 milligrams will actually reach your bloodstream.

There are two main reasons why this happens. First, CBD is hydrophobic, meaning that it is not very water-soluble. In the same way that oil does not like to mix with vinegar, CBD does not like to stay in your bloodstream. Instead, it rapidly diffuses out of your blood and accumulates into your fatty tissues. Unfortunately, this significantly reduces the amount of bioactive CBD that can enter your systemic circulation, allowing for less CBD to be carried to its active sites in your body and thus lowering its overall bioavailability.

Second, when an organic compound like CBD enters your gut, it has to pass through the liver before it enters your circulation. During this transition, the liver will actively reduce the amount of CBD, either through absorption or through chemical breakdown by liver enzymes. This phenomenon is called the “first-pass effect,” where passing through the liver reduces the concentration of bioactive compounds.

Maximizing CBD’s Effects: How to Offset CBD Loss by Vaporizing

 

There are a few different ways to offset these losses of CBD. For one, you can reduce the amount of CBD that dissolves out of your bloodstream by putting the CBD into a form that is more hydrophilicor water-soluble. However, this can only be achieved by complicated chemical means, such as through the use of cyclodextrins or liposomes. A more practical solution is to bypass the first-pass effect of oral administration entirely by utilizing vaporization.

During vaporization, CBD enters your lungs and diffuses directly into your bloodstream rather than passing through your gut and liver. This avoids the first-pass effect altogether, allowing nearly four times as much CBD to enter your circulation for a maximum bioavailability of roughly 50 to 60 percent. Essentially, this means you can achieve the same beneficial effects with a much smaller amount of CBD.

Not only that, but vaping will greatly decrease the amount of time it takes for the CBD in your body to become active, since you don’t have to wait for it to travel through your gut. By vaporizing a CBD e-liquid or high-CBD concentrate, you could potentially feel its effects 30 to 60 minutes faster. This makes vaping CBD an extremely efficient delivery method.

Of course, if you’re leaning towards embracing the vape life, make sure you’ve done your research on the concentrate you intend to consume. Without sufficient regulatory oversight in the emerging vape and cannabis industries, few companies have been able to produce a clear and homogenous CBD solution, so the milligram amount in CBD products is often inconsistent with the amount claimed on the label. Be sure to ask for both in-house and third-party test results from your chosen source to ensure you’re getting a quality product!

Andrew Pham currently serves as the Lead Scientist at CV Sciences, Inc. He was formerly the Lead Scientist at SC Laboratories, a prominent third-party analytical testing lab. He is also an executive member of the Cannabis Chemistry Subdivision (CANN) of the American Chemical Society

Sponsored by CV Sciences, Inc

 

CBD Oil Dosage –

General Advice to Assess How Much CBD to Take

Even with the wave of states legalizing medical marijuana, many physicians are still reluctant to prescribe cannabinoids because they are not sure what dosages to prescribe. After all, most medical schools never cover CBD Cannabidiol in their pharmacology courses. Medical scientists are just now developing dosing schedules for medical marijuana, medicinal hemp and their extracts, including CBD.

CBD-rich hemp oil comes in various concentrations and forms, including liquid hemp oil, hemp oil as a thick paste, oil in capsules, sublingual tincture drops or sprays, salves for topical use, edibles as in candy or gum and CBD vapor from vaporizers similar to e-cigarettes.

Everyone Is Different

What you will find on this page is meant to be a guideline, a starting point of reference. The fact remains that everyone is in a different place and will react differently to their CBD dosage. As serving size or dosage of CBD differs for each person, it is best to start small and gradually increase until you experience the desired result.

CBD Brands Confusing Dosage

CBD oil brands create a lot of confusion for consumers because they all have different standards. Many of them recommend way too much as a “serving” and others recommend too little. Because of this lack of standard during our review of individual CBD products, CBDOilReview.org created the COR Serving Standard to make things simple:

CBDOilReivew.org (COR) Serving Standard is 25mg of CBD taken twice a day.

It is also recommended that you try increasing dosage every 3-4 weeks by 25mg until symptom relief. And to decrease amount of CBD with any worsening of symptoms.

CBD Oil Dosing

Concentrations vary between preparations, ranging from 1 mg per dose to hundreds of milligrams. This makes it easy for consumers to get the dosages they need in a form they find easy to use.

CBD Dosages

Mayo Clinic suggests CBD dosages on scientific research, publications, traditional use, or expert opinion. Cannabinoid dosages and duration of treatment depend largely on the disease.

How Much CBD Oil Should I Take?

To increase appetite in cancer patients: 2.5 milligrams of THC by mouth with or without 1 mg of CBD for six weeks

To treat chronic pain: 2.5-20 mg CBD by mouth for an average of 25 days

To treat epilepsy: 200-300 mg of CBD by mouth daily for up to 4.5 months

To treat movement problems associated with Huntington’s disease: 10 mg per kilogram of CBD by mouth daily for six weeks

To treat sleep disorders: 40-160 mg CBD by mouth.

To treat multiple sclerosis symptoms: Cannabis plant extracts containing 2.5-120 milligrams of a THC-CBD combination by mouth daily for 2-15 weeks. A mouth spray might contain 2.7 milligrams of THC and 2.5 milligrams of CBD at doses of 2.5-120 milligram for up to eight weeks. Patients typically use eight sprays within any three hours, with a maximum of 48 sprays in any 24-hour period.

To treat schizophrenia: 40-1,280 mg CBD by mouth daily for up to four weeks

To treat glaucoma: a single CBD dose of 20-40 mg under the tongue. Doses greater than 40 mg may actually increase eye pressure.

According to CannLabs, the nation’s top full-service testing lab for cannabis products, there is no established lethal CBD dose. Consumers should read product inserts carefully to ensure they are taking the right amount of CBD, and talk to the prescribing physician about any questions or concerns.

How to Use CBD Oil – How to Take CBD Oil

CBD is most commonly taken orally in a concentrated paste or drops/ tincture format. To take CBD oil first hold it under the tongue to be absorbed in the mouth prior to swallowing. This step is important because some of the CBD taken will be broken down by the digestive system. Other oral methods include capsules, mouth strips, and edibles such as chocolate bars. Many people also enjoy using CBD oil via vaporizers or inhalers as this is a near instant delivery method that can be quite effective. Others use CBD oil by taking it through the skin via lotions, balms, creams or patches. There are many ways to take CBD oil, what matters most is trying a few different approaches and seeing what works. Again, everyone is different.

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